Novel Breast Density Technology Demonstrated at ECR 2015
March 16, 2015 — From Medimaging International staff writers.
A study using a new, automated, area based percent breast density measurement algorithm to assess mammographic breast density, using “for demonstration” full field digital mammography (FFDM) images, was presented at the 2015 European Congress of Radiology (ECR) in Vienna (Austria). The new breast density measures could be used by researches for the development of personalized breast screening protocols.
The study used face-validity to assess 1,823 images, and compared the algorithm to visual assessments by radiologists specializing in mammography. The radiologists assessed density using the FFDM images, and validated them as 5% increments using the Intraclass Correlation Coefficient (ICC), and the BIRADS 4level classifications using the Kappa Statistic. ICCs and Bland Altman plots were used to evaluate internal reliability and agreement between CC and MLO views on 2,372 for presentation FFDM images, and density measurements from left and right mammography views using the new algorithm.
The results demonstrated that the Densitas (Halifax, Nova Scotia, Canada) Research Edition algorithm showed almost perfect internal reliability between left and right views, and between CranioCaudal (CC) and MedioLateral Oblique (MLO) views of the same breast, and excellent agreement with radiologists' visual assessments. The BlandAltman plots showed narrow upper and lower limits of agreement between CC and MLO views, and negligible bias.